TP53 Multiplex Mutation Screening Kit
The Atila TP53 Multiplex Mutation Screening Kit identifies 295 possible mutation sites in a single well in a rapid and cost-effective manner.
Each kit includes 100 tests.
CE-IVD Certified. Meets EU standards for safety and performance.
TP53 Multiplex Mutation Screening Kit
Somatic mutations in the TP53 gene are one of the most frequent alterations in human cancers, and mutations occur in almost every type of cancer at rates from 38%–50% in ovarian, esophageal, colorectal, head and neck, larynx, and lung cancers to about 5% in primary leukemia, sarcoma, testicular cancer, malignant melanoma, and cervical cancer.
Cancer is a genetic disease with uncontrolled growth of abnormal cells. Some types of cancer are frequently associated with specific genetic mutations. Those mutations provide the biomarkers that allow more specific cancer treatments, known as targeted therapy.
Targeted therapy is a newer type of cancer treatment that offers patients the opportunity to use a drug that has a greater effect on cancerous tissue, reducing many of the side effects associated with standard therapy. Therefore, it is a critical step towards targeted therapy by identifying the cancer mutations with a precise and sensitive method.
Features Include
Technical Specs
Workflow Overview for the TP53 Multiplex Mutation Screening Kit
This section is for demonstrative purposes only and may be incomplete or inaccurate. Always refer to the product instructions for precise guidelines and directions.